Dr. Jen Manly is a co-principal investigator for NLS:72. She has co-led the 2021 follow-up of the High School & Beyond (HS&B:80) cohort. Her research on cultural, medical, and genetic predictors of cognitive aging and Alzheimer’s disease among African Americans and Hispanics has been funded by the National Institute on Aging (NIA) and the Alzheimer’s Association. Her research team has partnered with the Black and Latinx communities in New York City and around the United States to design and carry out investigations of structural and social forces across the life course, such as educational opportunities, discrimination, and socioeconomic inequality, and how these factors relate to cognition and brain health later in life. Dr. Manly was elected to the National Academy of Medicine in 2021. She served on the US Department of Health and Human Services Advisory Council on Alzheimer's Research, Care and Services from 2011-2015 and is a current member of the National Advisory Council on Aging.